Sustanon 250 course for gaining muscle mass

Testosterone is one of the important hormones in the human body, which is equally necessary for both men and women, since it performs various functions in our body, without which our health and general well-being would be at risk. The importance of this hormone is not without reason overestimated, since testosterone takes part not only in the development of the reproductive system in men and women, but also affects metabolic processes in our body, on which the functioning of the immune and hormonal systems, as well as the structure of bone and muscle tissue directly depends . It follows that in the case of a negative hormone level, a negative background occurs on many important processes in our body, which in turn affects our health and general well-being. Therefore, testosterone was artificially synthesized by scientists for use in medical practice, where it later found its use in sports.

Sustanon – what kind of drug is it and what is its difference from analogues?

Sustanon is a drug that consists of four testosterone esters and has similar properties as testosterone can have.
To put it more clearly, this is a drug that contains one active ingredient, but is broken down into 4 drugs, which are in the same commercial product and from the same raw materials, but differ from each other only in that each has a different prolonged effect, but on anabolic properties and this does not in any way affect the properties of the active substance itself. By purchasing such a product, you get the same testosterone as testosterone propionate or enanthate in terms of properties, but the effect of endogenous testosterone on the body from the Sustanon product occurs faster and at the same time leaves the body longer. Sustanon is sold under the trade names Sustaretard, Sustamed, Sustaver and others, and is a combination of the following testosterone esters:

  • propionate: 30 mg;
  • phenylpropionate: 60 mg;
  • isocapronate: 60 mg
  • Decanoate: 100 mg.

Among the excipients of sustanon: oil (usually peanut oil) as a solvent and benzyl alcohol as a preservative and antiseptic.

This combination of substances constantly maintains the level of male hormone in the blood at a high level.

The esters in Sustanol act as follows:

  • propionate is a fast ester, it begins to act within a few hours after entering the body and its main peak occurs after 12 hours;
  • phenylpropionate repeats the story of propionate, but with a delay of a day;
  • isocaproate is a medium-active ester that acts after phenylpropionate, which has a half-life of 9 days;
  • Decanoate is the longest ester and its active background lasts up to three weeks, and leaves the body for more than a month.

How fast does Sustanon work?

The speed at which the drugs act on the athlete’s body directly affects how quickly the final result will be achieved: muscle mass is increased, a new bar is taken or a new weight on the bar.

This is especially important on the eve of competitions, when athletes are trying to squeeze the maximum out of their bodies, especially if they are going for a record. Of course, after such grueling loads, athletes often undergo significant rehabilitation therapy, but not in all cases, I only in some of them. In addition, if we are talking about amateur athletes, then it makes no sense for them to exhaust their body so much if they work for themselves, and not for the Guinness Book of Records. However, everyone chooses independently how to formulate their steroid course, what drugs to take and what results to expect - the main thing here is to understand exactly how this or that drug will act on the body. Today we will look at Sustanon, because it is in great demand among Ukrainians and many novice athletes want to know more about this drug.

For those interested in the drug Sustanon, a special page has been prepared with all the necessary information about the drug, its method of action, recommendations for use and a lot of other useful points at https://steroids-shop.com.ua/product/147/, within the steroid store in Ukraine number one. Separately, I would like to say that it is the official distributor of the drug Sustanon on the territory of Ukraine, since it receives the drug directly from the manufacturer - therefore there is a guarantee of protection against counterfeiting, and the information provided on the site is fresh and relevant.

As for the speed with which Sustanon affects the body, the first thing to understand is that this is an injectable steroid drug, that is, one that is injected into the human body using a syringe. The drug immediately enters the bloodstream and begins to act, and then is broken down and excreted from the body through the internal organs. Experienced athletes state that the effect of the drug Sustanon is noticeable after the first dose, which is why this drug is so popular among those who want to see the effect “here and now” and do not want to wait long. However, the positive effects of the drug completely pay for this tactic.

Formacological properties of sustanon

As I already said at the beginning of the article, the active substance in such a product is common - it is testosterone and, accordingly, has all the inherent properties that relate to this hormone (androgenic anabolic effect and, accordingly, the effect on libido). Along with the positive effect of testosterone growth, it simultaneously exhibits an estrogenic effect.

Since the general properties and functions of sustanon do not distinguish it from other testosterone preparations, the binding to plasma proteins remains unchanged, which is 98%.

After injection, it gradually dissolves and smoothly enters the bloodstream, after which it interacts with cell and DNA receptors. The drug itself is metabolized in the liver and excreted mainly through the kidneys and slightly through the intestines.

The steroid profile of Sustanon is as follows:

  • Anabolic activity – 100%.
  • Androgenic activity – 100%.
  • Progestin activity – no.
  • The ability to aromatize is high.
  • Dehydrotestosterone derivative (DHT) - no.
  • Water retention is high.
  • The effect on the liver is low.
  • Blood pressure is high.
  • Acne – below average.
  • Release form: injections and tablets.
  • Duration of action – up to 5-6 days.
  • The detection time for doping control is up to 3 months.

What is Sustanon

An androgenic drug (that is, produced on the basis of the male sex hormone) Sustanon is an injectable solution based on four testosterone esters, which, when released into the bloodstream, are converted into a natural hormone. Testosterone is the main chemical regulating male sexual function. In adolescence, it ensures normal puberty, and throughout a man’s life he is responsible for:

  • normal functioning of the prostate gland;
  • production and quality of seminal fluid;
  • maintaining sexual desire;
  • maintaining the ability to achieve an erection.

Composition and release form

The drug Sustanon is available in the form of a solution for intramuscular injection, which is a yellow oily liquid. 1 ml contains 250 mg of the main active ingredient, auxiliary components - peanut oil, benzyl alcohol, nitrogen. The content of testosterone esters is presented below:

Substance Content in 1 ml of solution, mg
Testosterone propionate 30
Testosterone isocapronate 60
Testosterone phenylpropionate 60
Testosterone Decanoate 100

Sustanon 250 in a bottle

Pharmacodynamics and pharmacokinetics

During therapy with Sustanon, in men with reduced testosterone production, its concentration increases to clinically significant levels. The level of estradiol, androstenedione and dihydrotestosterone in plasma increases. The levels of globulin, which is responsible for binding sex hormones, decrease, and the levels of follicle-stimulating and luteinizing hormones return to normal. The effect of reducing the symptoms of testosterone deficiency is comprehensively achieved - sexual function is normalized (libido and erectile function are restored).

Those undergoing treatment experience an increase in muscle mass and bone mineral density (which causes athletes to take it as an anabolic steroid to accelerate muscle building). In the blood serum, the concentration of hemoglobin and hematocrit (red blood cell volume) increases, triglycerides, low- and high-density lipoproteins decrease. The level of liver enzymes and prostate specific antigen does not change.

There may be an increase in the size of the prostate gland, not accompanied by changes in function, and a decrease in body weight in obesity. Men with hypogonadism (impaired function of the gonads, accompanied by a decrease in the synthesis of sex hormones) and diabetes mellitus during the course of treatment should take into account that Sustanon-250 increases sensitivity to insulin and may lower glucose levels. A dose adjustment of insulin medications or a change in the dosage regimen approved by the attending physician is required.

The testosterone esters that make up Sustanon have different rates of action - the half-life of testosterone propionate is from 24 to 48, phenylpropionate - from 48 to 96 hours, isocapronate - 120-192 hours, decanoate - up to 10 days. The maximum concentration of natural testosterone in plasma, formed as a result of the hydrolysis reaction, is observed 1-2 days after intramuscular administration of the solution. Nonspecific binding to blood proteins is 97% and higher. Metabolized to estriol and dihydrotestosterone, excreted in the urine.

Indications for use

The drug Sustanon can be used by athletes involved in bodybuilding or weightlifting to accelerate muscle growth as an anabolic steroid. The drug must be used under the supervision of a trainer and attending physician. In medical practice, the drug is prescribed for a deficiency of male sex hormones during:

  • congenital or acquired hypogonadism (dysfunction of the gonads);
  • male menopause and other hormonal imbalances;
  • oligospermia (decreased amount of sperm released during ejaculation);
  • male infertility;
  • delayed puberty.

In some cases, the drug can be prescribed to women, with adjustment of the dosage and treatment regimen. Testosterone preparations are taken for complex treatment of hormonal imbalances caused by menopause, or with severe premenstrual syndrome, during the treatment of malignant tumors in the uterus or ovaries, with fibroids or inflammation and proliferation of the endometrium of the uterus. The selection of the drug is carried out by the attending physician based on the medical history and individual characteristics of the patient’s body.?

A man undergoes a cardio exercise test

History of use in medicine and sports

Sustanon replaced testosterone drugs, which were already used for hormone replacement therapy (HRT) in the mid-20th century.

The pharmaceutical company Organon took on the development of Sustanon. The company's goal was to develop a new drug based on several testosterone esters that could provide all their benefits under one product. After successful trials, the drug went on sale in the early 1970s under the trade name “Sustanon 250” and at the same time the drug quickly gained particular popularity in the world due to the use of the steroid in sports.

During pregnancy

During pregnancy or breastfeeding, a course of Sustanon alone or in combination with other drugs is strictly contraindicated, since changes in hormonal levels can have serious irreversible consequences for the formation of the child’s body. It is necessary to replace the androgenic drug with a drug from another pharmacological group.

Pregnant woman lying in bed

Positive effects

Sustanon has the same advantages and effects as each testosterone ester separately, namely:

  • an increase in the concentration of testosterone in the blood, which allows its use in medical practice and in sports;
  • the drug reduces pain in joints and intervertebral discs, and also promotes their recovery due to additional water retention and nutrition of tissues with necessary proteins and substances that are better retained during this period;
  • rapid increase in muscle volume up to 20% - this occurs due to additional retention of proteins in the tissues, which simultaneously leads to the accumulation of nitrogen in the muscles, which affects muscle volume;
  • progress in the development of muscle mass and strength indicators due to the same anabolic effect, which occurs due to the synthesis and accumulation of proteins, as well as substances necessary for the development of new muscle fibers due to their rapid nutrition and recovery after exercise;
  • anti-catabolic effect by reducing the level of cortisol in the blood;
  • increases the number of red blood cells in the blood, which means it improves the saturation of cells with oxygen and thereby increases endurance;
  • metabolism improves, which can be used for the purpose of losing fat, but this effect can only be obtained with a special approach to nutrition and training.

One of the important effects of sustanon is an increase in the concentration of testosterone in the blood, which is very important for those who use steroids, since endogenous testosterone helps to mask (compensate) the decline of the natural hormone from the negative impact of anabolic steroids on the production of natural testosterone in the blood.

Steroid profile Sustanon 250 (sustanon 250)

  1. Substance activity: up to 3 weeks
  2. Classification: anabolic/androgenic steroid
  3. Directions for use: by injection
  4. Dosages: men 500-1000 mg/week; women are not advised
  5. Acne: yes (in high dosages or in people with a predisposition)
  6. Water retention: high
  7. High blood pressure: yes
  8. Hepatotoxicity: no
  9. Aromatase: strong
  10. DHT(dehydrotestosterone) conversion: yes
  11. Decreased HPTA function (production of own testosterone): severely suppresses
  12. Detection time: 4 months (approximately due to the fact that the DC is constantly progressing in the search for methods for detecting prohibited substances; in addition, it depends on the athlete himself whether he is taking phenobarbital and furosemide to accelerate the elimination of the drug)
  13. Anabolic/androgenic ratio: 100/100

Effects of Sustanon 250

  • Rapidly increases body weight through protein synthesis
  • Has a good anti-catabolic effect
  • Improves appetite
  • Increases the number of red blood cells in the blood (hematopoiesis)
  • Increases oxygen transport
  • Affects increased endurance
  • Increases libido (on the sust course, of course)
  • Improves mood, feeling of confidence, desire to exercise. (noticeable when taking any androgenic drug)

Side effects of Sustanon

Since the drug has similar properties as other testosterone products, you may also encounter negative consequences when using Sustanon and have the following body reactions if you leave everything to chance and do not monitor your health indicators:

  • increase in blood pressure;
  • excess water retention, swelling, rapid weight gain due to estrogenic effects;
  • female type obesity;
  • the appearance of symptoms of gynecomastia in men;
  • prostate hypertrophy;
  • baldness;
  • acne;
  • increased blood cholesterol levels;
  • increased body temperature;
  • weakening of luteinizing and follicle-stimulating hormones;
  • decreased production of natural testosterone;
  • testicular atrophy;
  • possible aggressive behavior and irritability;
  • sleep disturbance;
  • pain and bruises at injection sites;
  • increased male pattern hair growth;
  • deepening of the voice;
  • Women may experience menstrual irregularities, deterioration of ovarian function, possible atrophy of the mammary glands and hypertrophy of the clitoris.

To minimize the risks of all kinds of reactions and consequences, it is important to monitor your health indicators during the course, as well as undergo body checks before and after.

Before starting the course, you need to pay special attention to the rules for performing injections. You can find all the rules and important topics regarding the course of steroids in the “Health” section or follow this link:.

How to inject Sustanon 250 in bodybuilding

Sustanon 250 solo course (without additional combined use with other anabolic steroids) should be carried out according to the following recommendations:

  • Can only be used by men; women are not recommended to use long testosterone esters, as it will be difficult to control side effects if they occur
  • Women use Sustanon in extremely rare cases, only if they are already advanced users and do not worry about their reproductive functions and appearance
  • Optimal dosages range from 250 to 500 mg of the drug once a week
  • The optimal length of use for a man is up to 10 weeks, if the course of Sustanon 250 involves longer use, then from the 10th week of use human chorionic gonadotropin should be added, 500-25,000 units per week, no more
  • The classic aromatase inhibitor, anastrozole, is used if side effects similar to a sharp increase in estrogen occur during use (swelling occurs, nipples begin to itch)
  • It must be taken 2-3 weeks from the start of the course, half a tablet every other day, and finished 1-2 weeks before the start of post-cycle therapy (after the last injection of the drug, aromatase inhibitors are removed, and PCT is carried out after 2-3 weeks)
  • At the same time, it is recommended to monitor hormonal indicators, primarily estradiol - before the course, during and after the course, as well as after PCT
  • The easiest way to perform PCT is to take tamoxifen 20 mg for one month, then 10 mg for the second month
  • Additionally, during PCT it is recommended to use a lot of sports nutrition, testosterone boosters or tribulus, at least 1000 mg per day, for 1 month, hepatoprotectors for 1 month (but in no case during the course, hepatoprotectors are harmful during the use of steroids)
  • Vitamins will not interfere: E in the amount of 200-300 mg, selenium 50-100 mcg, zincteral one tablet per day, ascorbic acid - 500 mg per day, nicotinic acid 100-150 mg per day
  • It is recommended to drink choleretic drugs, how to take: holosas, 2 tablespoons per day, you can also replace holosas with flamen or pumpkinol, if the user is not recommended to eat foods rich in sugar
  • It is also advisable to take fish oil to avoid increased levels of harmful triglycerides.

Effects obtained during the solo course:

  • Increasing muscle mass with a well-structured diet, otherwise it will be very flooded with water, which will go away at the end of the injections, and nothing will be left of the gained mass except fat
  • Anti-catabolic processes
  • Increased sexual desire
  • A good appetite
  • Improving endurance due to increased hematopoiesis.

Sustanon solo course and its disadvantages

I would like to note right away that testosterone injections to women for the purpose of physical development are highly undesirable, since the positive effects of such a course will be incommensurate with the significant risks that the female body will certainly be affected. If a woman approaches such a course, then it is necessary to take into account all the risks and work under the supervision of a specialist. Another question is if it is used for the purpose of replacement therapy and is monitored accordingly.

For men, the Sustanon solo course can be considered as the first or not the first course, if it so happens that you have no desire to combine several drugs at once or the goals are not bodybuilding at all, but for example hand-to-hand sports, crossfit and other functionality, where it will be enough solo course for the first time.

If we consider the first experience of use, then it will be enough to take a course of injections for 10 weeks and then make a decision about leaving the course or continuing at the same dosages or changing something, maybe adding additional drugs to the course or leaving everything as is.

For beginners, a dosage of 400 mg is suitable. per week, which it is advisable to divide and place twice a week to ensure a more even background, since the drug contains short esters. Since you are planning to use the drug for non-medical purposes and additional hormonal fluctuations will be of no use, short esters in the finished product should be taken into account. After completing the course, you must perform PCT. Therapy should be started a month after the injections are stopped, since Sustanon contains testosterone decanoate ester, which can leave the body even up to six weeks. PCT can be done with tamoxifen or Clomid. PCT schemes are available on the website in the “Health” section or via the link:

Disadvantages of the Sustanon solo cycle

Among the disadvantages of a solo cycle with Sustanon, it is worth noting the fact that significant results in terms of muscle growth cannot be obtained without combining testosterone with other anabolic drugs, which can further enhance the anabolic effect when used. You are now thinking that you can increase the testosterone dosage by 2-3 times or more in order to neutralize this loss of anabolism without resorting to mixing different drugs, but alas, your focus is doomed to failure, since increasing testosterone dosages above the recommended ones will only lead to the development of most side effects, since testosterone is a fairly androgenic drug and increased androgenicity brings with it a lot of troubles. Therefore, combining Sustanon with other steroids allows you to get more results with the same total dosage and with less side effects due to the absence of large dosages of testosterone.

Application of Sustanon 250

Taking Sustanon for men:

In therapeutic doses, Sustanon 250 is prescribed in doses of 250 mg every third week. For people involved in sports, the dosage ranges from 250 to 750 mg per week (usually divided into two doses per week), over a 4-8 week course. This is quite enough to increase muscle mass and strength.

Sustanon, as a rule, is used in mass gain courses, when the quality of the mass gained is not very interested. For these purposes, Sustanon is considered a very useful drug.

Taking Sustanon for women:

Sustanon 250 is not recommended for use by female athletes, due to the fact that its benefits will be less than harm.

Side effects of Sustanon 250

Rapid aromatization to estradiol. Elevated levels of estrogen can cause side effects such as fluid retention in the body, increased body fat and gynecomastia.

In order to prevent aromatization, various drugs can be used: mesterolone (Proviron, Mesviron 25, Provimed, Provirol-25, Proviron-25 Bayer), anastrozole or exemestane, in any case, at a dose of 250 mg of sustanon per week, neither Proviron, nor anastrozole (anastrozole) nor exemestane are recommended to be taken. Anti-estrogens such as clomed or tamoxifen may be useful after a course of PCT in order to avoid the rebound phenomenon.

It should be remembered that the higher the dose of testosterone in the body, the stronger the side effects will appear. An increased level of testosterone causes: acne, increased hair growth, baldness (only possible when a person genetically has poor protection of the hair follicle from dihydrotestosterone, dihydrotestosterone itself appears as a result of the conversion of testosterone into it, you can prevent baldness by taking finasteride, this drug prevents testosterone from being converted in dihydro, but it (dihydro) has an important function - sexual desire, so men who take finasteride have weakened libido), all these are androgenic side effects (most often with individual predisposition). In addition, the side effects of Sustanon 250 include: worsening of diagnosed prostate cancer, polycythemia (an increase in the number of red blood cells, which increases endurance, as well as muscle pumping during training, but thickens the blood, makes it viscous, which increases blood pressure and stress on the heart), myalgia (rarely) - muscle pain of various localization and origin, oligospermia (the number of live sperm decreases when compared with the norm), a decrease in ejaculate volume, and in the case of sensitivity of prostate tissue to dihydrotestosterone - prostatic hypertrophy.

Indications for medicinal use Sustanon 250

Testosterone replacement therapy in men for pathological conditions associated with primary and secondary hypogonadism, both congenital and acquired; restoration of libido after urogenital operations.

Contraindications for medicinal use Sustanon 250

Known or suspected prostate or breast cancer; hypersensitivity to any component of the drug; children under 3 years of age (as the drug contains benzyl alcohol).

Prescribed with caution: in boys in the prepubertal period in order to avoid premature closure of the epiphyses and premature puberty; chronic heart failure, renal and/or liver failure to avoid the development of edema; diabetes; prostatic hypertrophy with symptoms of urinary retention; sleep apnea, as well as risk factors such as obesity and chronic lung disease; childhood.

Combination of Sustanon with other steroids

Since Sustanon is a mixture of testosterones, and testosterone is an important hormone that you would not want to keep near zero for the entire period of the steroid cycle, it is logical to combine it with other anabolics throughout the entire period of their use.
Moreover, without testosterone injections, it is generally not recommended to take courses of anabolic steroids, since they help to reduce testosterone production against the background of hormonal changes during this period and at the same time get all the consequences of such a drawdown one-to-one. One of the most common combinations is the use of sustanon with any tablet drugs and nadrolone decanoate. Depending on your preferences, you can combine a course of Sustanon with drugs that have a fast and long half-life.

As such, there are no strict combination rules and you can combine any drugs with Sustanon if your soul asks for it and your hands itch. And if you strive for a more logical and competent use, then it is advisable to plan the course from 10 weeks, and select drugs equal in duration of action to sustanon (based on esters enanthate, decanoate, undecanoate, etc.), where in addition you can also add drugs with a short half-life . An example of a combination is as follows: Sustanon 500 mg/week. 1-12 weeks + masteron enanthate 600 mg/week. 1-12 + turinabol 40 mg/day for 5-12 weeks. Or create a course only based on Sustanon, where the first half of the course is combined with tablet versions (17-alpha), and the second half of the course includes injections with a short period of action (Masteron propionate, nadrolone phenylpropionate, trenbolone acetate). For example, Sustanon 500 mg/week. 1-12 weeks + Danabol 40 mg/day. 1-6 weeks + masteron propionate 100 mg. h/day 7-13 weeks.

* Important! Always keep in mind that Sustanon contains long testosterone esters, which can leave the body from four to six weeks, which in turn will affect the start of PCT, which makes no sense to start as long as androgens are in the body.

Instead of sustanon, you can use other testosterone esters: propionate, enanthate, cypionate, etc. Sustanon, however, is for more experienced people who have tried several esters separately.

The use of Sustanon and other anabolic steroids should be supervised by a specialist or doctor who is familiar with the use of pharmacology for sports purposes. Only in this case will it be possible to minimize the negative consequences and obtain the expected result.

Examples of combined courses

  1. Sustanon 250-500 mg once a week and Turinabol 30-40 mg per day. Duration: 6-8 weeks.
  2. “Ten-week course”: the first 8 weeks - “Sustanon” 250-500 mg once a week and “Methane” 30-40 mg per day, the last 2 weeks “Sustanon” and “Methane” are replaced with “Testosterone Propionate” 50-100 mg every other day and Trinabol 40 mg per day.
  3. Sustanon 250-500 mg once a week and Nandrolone 200 mg per week. Duration 6-8 weeks.
  4. "Sustanon" 250-500 mg and "Boldenone" 400-800 mg once a week + "Turinabol" 40 mg or "Methane" 30 mg per day. Duration 8-10 weeks.
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