Methylsulfonylmethane (MSM): benefits and applications

Characteristic

Methylsulfonylmethane is designated by the short abbreviation MSM and plays a significant role in the normal functioning of the body. Most often, this substance can be found in combination with the main chondroprotectors. It is MSM that increases the ability of the cell membrane to transmit nutrients necessary for cell health. Sulfur, which makes up methylsulfonylmethane, is an excellent conductor for most of the components needed by all components of the musculoskeletal system. Thanks to its action, the synthesis of hemoglobin, collagen and keratin, which are necessary to maintain the elasticity of connective tissue, is accelerated.

Methylsulfonylmethane (MSM): properties

Unknown to most of us, sulfur is one of the five essential elements of life. Sulfur is an essential component in human nutrition. It is found in every cell of the body and is structurally and functionally important for 150 compounds, including hormones, enzymes, antibodies and antioxidants. MSM provides an essential portion of the sulfur needed for a number of compounds in the body.

Methylsulfonylmethane is one of the main components of various compounds and processes in the body, and is also necessary for the synthesis of collagen, immunoglobulin and enzymes. In the body of MSM :

Maintains flexibility and permeability of cell membranes, promoting efficient metabolism.
Ensures connective tissue health and collagen formation.
Provides the body with the raw materials it needs to create new cells and to repair and replace damaged tissues and organs.
Features in energy production, as a component of insulin and a prerequisite for normal carbohydrate metabolism.
It is important in maintaining the acid-base (pH) balance in the body.
It is an activator of thiamine, vitamin C, biotin and pantothenic acid.

Meaning

MSM has the following effects:

promotes cellular metabolism;
has a detoxifying effect;
improves oxygen exchange in cells;
is a powerful antioxidant;
participates in the process of bile production;
increases the body's protective properties;
controls blood sugar levels;
strengthens intercellular connections of bone and cartilage tissue;
regenerates joint cells and joint fluid;
has wound healing and anti-inflammatory effects.

pharmachologic effect

MSM has a positive effect on health and helps stabilize the functioning of internal organs. Accelerates muscle mass gain, stimulates cellular nutrition, improves the condition of ligaments, joints, connective tissue, and increases blood circulation. MSM affects nerve impulses, reducing discomfort and pain. For this reason, it is used by many athletes during active sports activities. Methylsulfonylmethane naturally restores muscles after intense physical activity. This occurs by reducing lactic acid and eliminating the inflammatory process in tissues. The component has a positive effect not only on joints, but also on the condition of skin and hair.

It is involved in the production of collagen and keratin and increases cell viability. MSM takes part in the synthesis of antioxidants, increases cell permeability, which enhances the ability to easily remove toxins and lactic acid. In complex glucosamine-chondroitin-msm products, the result is achieved due to the properties of each component. During the administration, cartilage tissue is restored, tension and pain are eliminated. The synthesis of collagen and hyaluronic acid is stimulated, calcium balance is regulated, wound healing and recovery after fractures are accelerated. In addition, cholesterol levels decrease and blood circulation improves.

Application in sports

If you look at the composition of complex supplements for strengthening the musculoskeletal system of athletes, you will find methylsulfonylmethane in almost every one. Most often it is taken together with chondroitin and glucosamine, as it improves their permeability into the intracellular space. With regular training, as well as following certain diets, the production of these substances decreases, so it is necessary to provide them with an additional source.

Methylsulfonylmethane helps prevent inflammation in the joints, and also prevents the drying out of the joint capsule, accelerating the production of the fluid contained in it.

The regeneration of cartilage cells is also reduced due to an insufficient amount of sulfur, since chondroprotectors simply cannot pass through the dense membrane.

Sulfur is an important component of protein, which acts as a building block for all elements of the body's connective system. It helps muscle fibers recover faster after heavy exertion.

Reviews of Methylsulfonylmethane

Reviews about dimethyl sulfone are mostly positive:

“... I bought this supplement because of seborrhea, I read somewhere that it could help. I received comprehensive treatment and also selected a good shampoo and conditioner. After the course everything returned to normal”;
“... I drink the medicine and give it to my mother so that my joints don’t hurt or creak. It seems to help, the main thing is that there are no side effects”;
“... I bought a supplement to improve my health; after I turned 30, my joints began to bother me. I took it along with chondroitin, but for some reason I developed an allergy and a rash all over my body. I had to stop taking it."

Contents in products

Sulfur is found in the following foods:

eggs;
legumes;
meat;
cereals and cereals;
dairy products;
green and red vegetables;
fish.

The daily requirement of MSM is from 500 to 1200 mg. It is not always supplied with food in the required quantity, so doctors recommend the use of specialized supplements.

In what cases can MSM help?

The organosulfur compound helps best in the first stages of illness. It is recommended to use methylsulfonylmethane in the dosages specified in the instructions for the drug. Supplements will be useful for older people, since the amount of sulfur steadily increases with age and inflammation, pain, and grinding in the joints begin to plague them.

Pain in joints and ligaments often appears as a result of intense physical stress. This is especially evident when practicing strength sports disciplines. Methylsulfonylmethane will help cope with the consequences of such regular training. This is due to the fact that the compound helps relieve inflammation and promotes the regeneration of ligaments and cartilage.

It should be understood that training during periods of exacerbation of pain must be stopped and resumed after recovery. Otherwise, taking supplements will not bring any results or the athlete may be injured again.

Indications for use of MSM for joints

Indications for use of msm:

For complex treatment of osteoarthritis and joint pain
Reduces digestive problems and helps get rid of many intestinal problems
Helps get rid of blackheads and acne
Restores muscles and provides relief after regular and strenuous training or physical activity.
Helps improve hair growth
Allows you to slow down the destruction of joints due to arthritis and arthrosis

Thus, sulfur helps improve the condition of bones and joints. The fact is that the main cause of joint problems is a decrease in collagen production, which is common in people aged 35-40 years. First, the skin becomes flabby, then this affects the condition of the entire body, including bones. Accordingly, organic sulfur helps improve the condition of joints and actively fights many diseases.

Initially, after taking the drug, swelling and pain decrease. In addition, the progression of arthritis slows down. Of course, organic sulfur is not able to completely cure arthrosis, because these are degenerative processes that lead to tissue destruction. But, nevertheless, it is able to slow down the process of destruction of cartilage and bone, improve the patient’s condition, and relieve him of pain.

MSM Evalar

Methylsulfonylmethane

Studies29) have used a dosage of 4-6 g of MSM, with some reports using dosages up to 20 g (not in clinical studies). Based on body weight, the guideline (not mandatory, but recommended by supplement manufacturers) is about 0.06 g/kg and is expected to be safe even at 10 times this dose (although 100 times the dose or 6 g/kg body weight in humans is toxic )[38]. One systematic review found two studies evaluating the effects of MSM on osteoarthritis, the study used a dosage of MSM 1500 mg (either alone or with 1500 mg glucosamine) daily for 12 weeks; although the primary outcome (3 point reduction in Lequesne index) was not recorded, it suggests greater pain reduction in all treatment groups compared with placebo, with no significant differences between glucosamine and MSM30). Another study used a higher dose of MSM (2 g daily for 2 weeks followed by 6 g for 10 weeks) which confirmed the pain-reducing effect associated with MSM, and a study using 3.375 g MSM for 12 weeks in patients with knee osteoarthritis showed a 20% reduction in symptoms with MSM (14% placebo reduction) and a 21% reduction in pain with a 9% placebo increase. The review noted that the magnitude of benefit with high-dose MSM (visual analogue scale reduction of 13.6 mm) was less than that for the pharmaceutical drug Celecoxib (28.6 mm31) and also noted that this pilot study was not quite statistically powerful. A study not presented in this review had a similar magnitude of pain reduction (15 mm for general symptoms), and all studies using MSM had high variability and confidence intervals. Other studies of arthritis-related pathologies using MSM noted that 5 mg MSM plus 7.2 mg boswellic acid (Boswellia serrata dietary supplement) failed to outperform placebo in reducing symptoms while reducing the need for analgesics (suggested). or limited effectiveness)32). At present, although there is speculation surrounding the treatment of MSM for osteoarthritis, there is little evidence that it is superior to other agents (celecoxib, glucosamine, acetaminophen). MSM supplementation shows variability and magnitude of effect similar to glucosamine sulfate, but with less overall evidence.